Luxury Cape Town, Garden Route & Safari Self-Drive

From $5,900.00 p/person

Explore South Africa’s scenic coastline on this luxurious self-drive holiday.

Explore the very best of Cape Town when based at Camissa House boutique Hotel at the base of Table Mountain, and experience the city’s sublime restaurants, wine farms, beaches and mountain trails. 

From Cape Town, you’ll make your way up the tranquil Garden Route, along the Southern Cape Coast through to Plettenberg Bay, where you’ll find a secret abode at Tsala Treetops, a luxury hotel set above an expansive indigenous forest. Get adventurous with zip-lining or kayaking, or kick back and relax with a spa treatment, fine dining or beach walk. 

You’ll then head into the Eastern Cape for a malaria-free Big 5 luxury safari at Kwandwe Private Game Reserve. Enjoy twice-daily game drives, nature walks and fishing, and discover the wildlife and birdlife of this diverse part of South Africa. 

This trip is ideal for couples or honeymooners, but can be tailored to suit families of all ages. 

Best Time to go

  • Mar
  • Apr
  • May
  • Jun
  • Jul
  • Aug
  • Sep
  • Oct
Luxury Cape Town Garden Route and Safari Self Drive

Your Itinerary

3 nights in Cape Town

Arrive in spectacular Cape Town, South Africa’s most popular city and the perfect base from which to start your luxury self-drive holiday. You’ll enjoy a private road transfer from the airport through to Camissa House, the perfect base for your stay in The Mother City. After a hearty breakfast, you can set out to explore! Your car rental will be delivered to your hotel, so you can choose your route.

Head up Table Mountain via the cable car and descend via one of the top mountain trails, or embark on a trip to Robben Island. A scenic drive around the Cape Peninsula has its delights: see the penguins at Boulders Beach, stop for coffee in Simon’s Town and marvel at the views from Chapmans Peak.

Time in Cape Town should not be without a visit to either the Constantia or Cape Winelands; with so many award-winning estates and wineries, you’ll be hard-pressed to choose! The city is also filled with a variety of fine dining restaurants, relaxed eateries and streetfood options, while local markets are also highly popular.


Enjoy delicious Full English and continental breakfasts and High Teas served daily, and dinner transfers to top local restaurants.

Camissa House


Camissa House

This stylish boutique hotel is situated at the base of Table Mountain, and offers spectacular city and mountain views. Ideal as a base to explore Cape Town, Camissa House also offers a rooftop bar, entertainment area and an infinity pool. 

Camissa House

3 nights in Plettenberg Bay

Leave Cape Town behind and enjoy a scenic drive up the famed Garden Route to Plettenberg Bay, where you’ll enjoy 3 sumptuous nights at Tsala Treetops, a luxurious boutique hotel tucked into the heart of an indigenous forest.

On your way, you’ll meander along the Cape Whale Coast, then along the N2 towards Mossel Bay, Wilderness and Knysna. This part of the country is well known for its incredible sea views, eateries, and beautiful natural scenery of forests, fields, mountains and beaches.

Spend your time in and around Plett – as it’s commonly called here – with visits to local animal sanctuaries, walking the beautiful beaches and going fishing or kayaking in one of the lagoons or rivers. From zip-lining through the forest, to delectable seafood dinners there’s plenty to do, see and experience.


Meals at Tsala are presented in the glass-walled dining room, or out on the spectacular dining deck, suspended above the forest floor. A variety of top restaurants in the area can also be enjoyed; ask the Tsala staff for their best recommendation.

Tsala Treetops


Tsala Treetops

Set amidst the treetops of an indigenous forest, Tsala Treetops is a luxurious boutique hotel that captures the spirit of Africa. Both intimate and expansive, you’ll truly feel like you’re floating above a canopy. Each luxury suite is constructed out of natural materials, with beautiful forest views. 

Tsala Treetops

4 nights at Kwande Private Game Reserve, Eastern Cape

From the Garden Route, you’ll drive towards Port Elizabeth and then head into the interior to Kwandwe Private Game Reserve, a scenic Big 5 game reserve in the heart of the Eastern Cape Province. You’ll spend the next few days at Kwandwe Great Fish River Lodge, a luxurious safari escape with beautiful river and landscape views.

Enjoy daily dawn and dusk game-drives in custom 4×4 safari vehicles, with your own experienced ranger and tracker. The reserve is home to the Big 5 (elephant, buffalo, lion, leopard and rhino), but there are also cheetah, giraffe, wildebeest and a variety of antelope, as well as some elusive nocturnal animals to be spotted.

You can also try your hand at fishing (large mouth bass in the dam or river), or head out on either a Big Game Safari Walk or Interpretive Bush Walk. Relax with a spa treatment or simply take time out with a pair of binoculars on the main deck.

On your final day, you’ll drive to Port Elizabeth Airport to return your rental car and catch your outgoing flight (either via Cape Town or Johannesburg).


Delicious African-inspired meals are served in the candle-lit dining room or out in the lantern-filled boma under the starlit sky.

Kwandwe Great Fish River Lodge


Kwandwe Great Fish River Lodge

With spectacular views of the Great Fish River from the indoor-outdoor living areas, this lodge is all about embracing the environment. From your own private plunge pool to the thatched terrace, king-size luxury bed and beautifully appointed bathroom, your time here is spent in luxury. Experience incredible game-drives at dusk and dawn, and keep a look out for the Big 5. 

Kwandwe Great Fish River Lodge


Private road transfer from Cape Town International Airport to Camissa House
Car rental for 10 days (includes GPS, delivery at Cape Town Hotel, drop off at Port Elizabeth Airport)
3 nights at Camissa House in a Luxury Suite on a bed & breakfast basis
3 nights at Tsala Treetops in a Luxury Suite on a bed & breakfast basis
4 nights at Kwandwe Great Fish River Lodge in a Luxury Suite on a full board basis (Including all meals, 2 game drives daily, walking safari and local drinks)


International flights, air reservations and airport taxes 
Transfers not mentioned in the itinerary 
Activities not mentioned in the itinerary 
Activities specified as additional / optional in the itinerary 
Meals and drinks not mentioned in the itinerary 
Travel insurance 
All items of a personal nature 


Our rates are per person sharing unless expressly identified. Please treat all pricing as a guide only: All rates are an estimation, subject to availability and may change without notice. Single supplements may apply. Enquire now or speak to one of our expert Travel Planners for updated rates. 

Ready to plan your trip?

Begin your journey with us


Explorer is the inbound division of Grosvenor Tours, part of Cullinan Holdings, a member of The Travel Corporation family of brands. 


We are the industry leaders in private, tailor-made luxury travel, leveraging over 60 years of experience in creating bespoke safaris in Africa. 


We’ve personally experienced each destination and luxury safari lodge to ensure we offer only top quality, exclusive & authentic African encounters.

Similar Trips